LeukoStor™ – 30mL - Atelerix

LeukoStor™ : Store and transport your leukapheresis material

LeukoStor™ – 30mL

£1,105.00
Title
  • International Delivery Available

Title

Includes gelBASE beads, non-crosslinked gel and dissolution buffer for the in situ encapsulation, storage and release of leukapheresis material in blood bags.

WHY CHOOSE LEUKOSTOR?

Preserve your leukapheresis material for up to 5 days.

Move your samples across the world whilst maintaining the viability, phenotype and function of key immune cell populations.

Your cells can be easily encapsulated, shipped and released in a cost-effective manner.

Available in a bag format and can be handled in a closed system

QUICK AND EASY TO USE

Encapsulate your sample by simply adding a gel concentrate to your leukapheresis material and transferring to a bag containing gelation beads. After a few minutes, the apheresis material with gel in situ and is ready for storage or shipment. When ready to be used a gentle Dissolution Buffer is added to dissolve the gel, the beads are filtered out and the apheresis material ready to use. 

ENCAPSULATION PROCESS

PRODUCT CODE
 

COMPONENTS
 

UNITS
 

UNIT VOLUME
 

APHERESIS
VOLUME TO ADD

 

 

LS - 30S-03

 

 

 

 

LS - 30S-06

 

 

 

 

LS - 30S-12

 

 

 

 

LS - 30S-24

 

 

 

 

LS - 30S-50

 

 

Bag A (5x Gel A)

Bag B (GelBase beads)

Bag C (Dissolution Buffer)

Blood administration set

Line clamps

Bag A (5x Gel A)

Bag B (GelBase beads)

Bag C (Dissolution Buffer)

Blood administration set

Line clamps

Bag A (5x Gel A)

Bag B (GelBase beads)

Bag C (Dissolution Buffer)

Blood administration set

Line clamps

Bag A (5x Gel A)

Bag B (GelBase beads)

Bag C (Dissolution Buffer)

Blood administration set

Line clamps

Bag A (5x Gel A)

Bag B (GelBase beads)

Bag C (Dissolution Buffer)

Blood administration set

Line clamps

3 bags

3 bags

3 bags

3 bags

9 units

6 bags

6 bags

6 bags

6 bags

18 units

12 bags

12 bags

12 bags

12 bags

36 units

24 bags

24 bags

24 bags

24 bags

72 units

50 bags

50 bags

50 bags

50 bags

150 units

7.5mL

30.0mL

45.0mL

-

-

7.5mL

30.0mL

45.0mL

-

-

7.5mL

30.0mL

45.0mL

-

-

7.5mL

30.0mL

45.0mL

-

-

7.5mL

30.0mL

45.0mL

-

-

30.0mL

-

-

-

-

30.0mL

-

-

-

-

30.0mL

-

-

-

-

30.0mL

-

-

-

-

30.0mL

-

-

-

-

APPLICATIONS

Preserve T cell viability 

LeukoStor™ preserves T-cell yield and viability after 5 days of storage at 25°C. Left - Total T-cell yield (CD3+ cells as a % of total single CD45+ cells) at day 5 following storage was improved by LeukoStor compared to the no-gel control (NGC) which represented non-manipulated LRSC material. Right - The quality of T cells from leukocone material (used as an apheresis starting material surrogate) severely deteriorated when left unprotected over 5 days at 25°C. 

Maintain leukocyte composition in apheresis 

Assessment of cell composition of apheresis material after 5-day storage in LeukoStor™.

Post-rest recovery of PBMCs isolated from leukocone material 

Post-rest recovery of PBMCs isolated from leukocone material after storage in LeukoStor for 5 days at 25C. LeukoStor improves the post-rest recovery, viability, and metabolic activity of PBMCs compared to the no-gel control. 

RESOURCES

Whitepaper - Application of LeukoStor to CAR-T Cell Therapy Manufacturing

View Paper

PROTOCOLS

Download Protocol