LeukoStor™ – 10mL - Atelerix

LeukoStor™ : Store and transport your leukapheresis material

LeukoStor™ – 10mL

£475.00

Title

International Delivery Available

Title

Includes gelBASE beads, non-crosslinked gel and dissolution buffer for the in situ encapsulation, storage and release of leukapheresis material in a vial.

WHY CHOOSE LEUKOSTOR?

Preserve your leukapheresis material for up to 5 days.

Move your samples across the world whilst maintaining the viability, phenotype and function of key immune cell populations.

Your cells can be easily encapsulated, shipped and released in a cost-effective manner.

Available in a bag format and can be handled in a closed system

QUICK AND EASY TO USE

Encapsulate your sample by simply adding a gel concentrate to your leukapheresis material and transferring to a bag containing gelation beads. After a few minutes, the apheresis material with gel in situ and is ready for storage or shipment. When ready to be used a gentle Dissolution Buffer is added to dissolve the gel, the beads are filtered out and the apheresis material ready to use.

ENCAPSULATION PROCESS

Timings differ between kit size:

LeukoStor™ 10 mL:
encapsulation – 20 min
release – 30 min

LeukoStor™ 30 mL:
encapsulation – 60 min
release – 45 min

LeukoStor™ 70 mL:
encapsulation – 60 min
release – 45 min

PRODUCT CODE

COMPONENTS

UNITS

UNIT VOLUME

APHERESIS
VOLUME TO ADD

LS - 10S-03

LS - 10S-06

LS - 10S-12

LS - 10S-24

LS - 10S-50

Bag A (5x Gel A)

GelBase beads

Dissolution Buffer

Cell Strainer

Bag A (5x Gel A)

GelBase beads

Dissolution Buffer

Cell Strainer

Bag A (5x Gel A)

GelBase beads

Dissolution Buffer

Cell Strainer

Bag A (5x Gel A)

GelBase beads

Dissolution Buffer

Cell Strainer

Bag A (5x Gel A)

GelBase beads

Dissolution Buffer

Cell Strainer

3 bags

6 units

6 bags

12 units

12 bags

24 units

24 bags

48 units

50 bags

100 units

2.5mL

10.0mL

20.0mL

-

2.5mL

10.0mL

20.0mL

-

2.5mL

10.0mL

20.0mL

-

2.5mL

10.0mL

20.0mL

-

2.5mL

10.0mL

20.0mL

-

10.0mL

-

10.0mL

-

10.0mL

-

10.0mL

-

10.0mL

-

APPLICATIONS

Preserve T cell viability

LeukoStor™ preserves T-cell yield and viability after 5 days of storage at 25°C. Left - Total T-cell yield (CD3+ cells as a % of total single CD45+ cells) at day 5 following storage was improved by LeukoStor compared to the no-gel control (NGC) which represented non-manipulated LRSC material. Right - The quality of T cells from leukocone material (used as an apheresis starting material surrogate) severely deteriorated when left unprotected over 5 days at 25°C.

Maintain leukocyte composition in apheresis

Assessment of cell composition of apheresis material after 5-day storage in LeukoStor™.

Post-rest recovery of PBMCs isolated from leukocone material

Post-rest recovery of PBMCs isolated from leukocone material after storage in LeukoStor for 5 days at 25C. LeukoStor improves the post-rest recovery, viability, and metabolic activity of PBMCs compared to the no-gel control.