Atelerix is looking to recruit two research and development scientists to help drive our product development. We’re looking for an Immunologist and a Histologist to expand the capabilities of our team. These essential roles within the R&D team will support the design, development and validation of products with a range of biologicals including different cell types, 3D culture models, and primary tissues.

Research and Development Scientist – Immunology

Essential Duties and Responsibilities:

Design and execution of experimental workplans that focus on the preservation of blood products and isolated immune cells. Knowledge of molecular and cellular biology, and specifically immune cell biology, is essential.

Duties include:

• Processing different types of human blood products (e.g. LRS cones, leukopaks & peripheral whole blood), including isolation of PBMC and immune cell subsets
• Phenotyping subsets of immune cells by performing immunolabelling and flow cytometry.
• Analysing flow cytometry data
• Handling and assaying the phenotype and function of lymphocytes, monocytes and macrophages
• Reviewing, collating, evaluating relevant literature
Writing and reviewing protocols
• Sourcing of cells/consumables
• Project planning
• Performing and writing risk assessments
• Conducting practical experiments
• Troubleshooting
• Data analysis and report writing
• Internal / external dissemination of results

Product Development

Design and execution of experimental workplans on generating new product formats to solve existing problems (e.g. integration with different cell culture formats & manufacturing processes)

• Product design
• Product evaluation
• Protocol construction

Essential Requirements:

• A PhD in a biological science discipline
• Extensive cell culture experience and/or handling primary cells/tissues
• Familiarity with a range of experimental and analytical techniques
• Experience in developing, optimising and executing biological assays, ideally in a commercial setting.
• Excellent written and verbal communication skills
• Hardworking and self-motivated
• Excellent problem-solving skills
• Legal right to work and reside in the UK

Desirable:

• Experience in culture and assay of primary blood cells/immune cells
• Experience with cell biochemical and metabolic assays
• Experience of working within a QMS (Quality Management System) framework
• Previous employment in the pharmaceutical or biotechnology industry would be an advantage
• Experience of working with industry partners and stakeholders
• Experience of grant writing and application processes

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Research and Development Scientist – Oncology/Histology

Essential Duties and Responsibilities:

Design and execution of experimental workplans that focus on the preservation of solid tissue biopsies. General knowledge of molecular and cellular biology is required; specific knowledge of tumour histopathology would be highly desirable.

Duties include:

• Handling and processing solid tissue samples for histology
• Performing standard (e.g. H&E staining) and specialised (e.g. IHC) histological techniques
• Viewing, imaging, and analysing histological data in an accurate and reliable manner
• Writing and reviewing protocols
• Sourcing of cells/consumables
• Project planning
• Carrying out and writing risk assessments
• Conducting practical experiments
• Troubleshooting
• Data analysis and report writing
• Internal / external dissemination of results

Product Development

Design and execution of experimental workplans on generating new product formats to solve existing problems (e.g. integration with different formats & manufacturing processes).

• Product design
• Product evaluation
• Protocol construction

Essential Requirements:

• A PhD in biological science discipline
• Extensive cell culture experience and/or handling primary cells/tissues/biopsies
• Familiarity with a range of experimental and analytical techniques, particularly associated with tumour histology
• Experience in developing, optimising and executing biological assays ideally in a commercial setting
• Excellent written and verbal communication skills
• Hardworking and self-motivated
• Excellent problem-solving skills
• Legal right to work and reside in the UK

Desirable:

• Significant experience of experimentation with tumour biopsies across the entire workflow: from collection & handling to processing and characterisation
• Knowledge of pathology, particularly cancer pathology
• Experience with cell biochemical and metabolic assays
• Experience of working within a QMS framework
• Working with industry partners / stakeholders, preferably from within industry itself
• Experience of grant writing and applications processes

About Atelerix Ltd
Atelerix is a UK-based company whose patented technology is transforming the storage and transport of living cells by enabling extended storage at temperatures between 4°C and 25°C while preserving their functional viability. The company’s customers are developing cell-based therapeutics, cell lines, organoids and assays for use in drug discovery and development. Atelerix products eliminate the need for complex ultra-low temperature logistics and potentially harmful freeze-thaw processes, providing greater quality, consistency of performance, flexibility, convenience and security as critical samples are shipped around the world.